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EcoCyto - Fluid shear stress calculator APK

最新版本 1.0 for Windows
更新 2017年October27日

信息

1.0 (#1)

更新 2017年October27日

APK档案大小 240.8 KB

Android 系统版本要求 Android 4.4+ (KitKat)

开发者 EcoCyto

类别 效率 (应用)

应用 ID com.fss.generator

开发者备注 Cheap, high throughput instigation of fluid shear stress on your cultured cells

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新功能

EcoCyto - Fluid shear stress calculator 1.0的新功能

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内容描述

Fluid shear stress (FSS) is known to modulate cell biology in multiple cell lineages.
Research groups investigating the role of FSS have previously relied on parallel plate flow chambers or cone and plate viscometers to instigate physiologically relevant degrees of FSS, however these approaches are expensive and low throughput.
In 2010, a fluid mechanics research group defined a mathematical model which describes the FSS instigated on a cultured cell monolayer when a culture dish of known dimensions, immersed in a known volume of fluid of known viscosity is rocked at a known angle and frequency.

This mobile application rearranges and optimises that model in a more user friendly format; i.e the user may select the degree of fluid shear stress they wish to simulate using the equipment they have in their laboratory. The app calculates the volume of fluid required to meet that target FSS, which varies depending on all other variables.
EcoCyto's fluid shear stress calcualator was validated agasint the original publications example data, and has been used to identify multiple effects of fluid shear stress (1 dyne/cm2) in a kidney cell line.

Requirements:
1. A cell rocker
2. Standard cylindrical tissue culture plates or dishes of any size.
3. An adherent cell line

References

X. Zhou, D. Liu, L. You, and L. Wang, “Quantifying fluid shear stress in a rocking culture dish.,” J. Biomech., vol. 43, no. 8, pp. 1598–602, May 2010.

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EcoCyto - Fluid shear stress calculator 1.0 APK - Windows 下载 - (#1, 240.8 KB)